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Introducing Yu Chen: Lush Prize Young Researcher 2016

The Lush Young Researcher Prize aims to recognise and reward those working to eliminate animal testing in science and cosmetics through their research. Yu Chen, from the Chinese Centre for Alternative Research, has won one of this year’s 13 prizes for his research into alternative tests for hygiene toxicology. 

Introducing Yu Chen: Lush Prize Young Researcher 2016

The Lush Young Researcher Prize aims to recognise and reward those working to eliminate animal testing in science and cosmetics through their research. Yu Chen, from the Chinese Centre for Alternative Research, has won one of this year’s 13 prizes for his research into alternative tests for hygiene toxicology.

Yu Chen works as part of the team at one of the leading in vitro (that’s tests in a petri dish or test tube) labs in China.

In China testing on animals is an entrenched part of safety testing. Yu Chen and his team want to make this a thing of the past, and are working towards a tiered testing strategy that would dramatically reduce the amount of animals used.

Yu Chen explains: “As long as our testing results database of eye irritation and skin irritation increase, we try to integrate the different methods to a tiered testing strategy.”

To do this Yu Chen aims to use a variety of in vitro tests on cell cultures to detect how a person’s body would react to different chemicals.

He says: “I want to build the skin sensitisation tiered testing strategy in our lab, based on the Direct Peptide Reactivity Assay (DPRA) and Human Cell Line Activation (h-CLAT) test  and the combination of Episkin TM 3D skin model with THP-1 cells.

“What’s more, if it is possible, I want to use genomics of 3D skin models to research skin sensitisation. When this is completed, the different solubility of substances could be quickly tested for skin sensitisation.”

But Yu Chen doesn’t want to stop there and hopes to continue to impact the field of alternative testing in China and the rest of the world.

“This is just the beginning. I will continue with research methods to strengthen animal welfare, thereby not only establishing testing methods that contain more extensive content, but are also more humane.

“We should focus on the development of non-animal testing using creativity and effort,” he suggests, in a bid to further mobilise the field of alternative testing.

 

Yu Chen, from the Chinese Centre for Alternative Research, has won one of this year’s 13 prizes for his research into alternative tests for hygiene toxicology.

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